Decentralized platform for connectomics data

Store, query, and share synapse metrics from electron microscopy datasets. Cloud-native, federated, and open to the community.

What is SynDB?

A cloud-native data platform for connectomic research that can be openly queried and externally contributed to, facilitating data access and collaboration across experimental and computational neuroscience.

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Query

Use SyQL, a structured query language designed for connectomics data, to search geometric, categorical, and relational data types across neuronal compartments.

Federate

Deploy on Kubernetes clusters and form a data federation across voluntary data centers. Contributors retain full data ownership with cite-able DOIs.

Analyze

Perform graph analysis, meta-analysis, and analytics on synapse, axon, dendrite, vesicle, and mitochondria datasets at scale.

Key Features

Built on a modern stack for performance, scalability, and accessibility.

Cloud-Native Stack

PostgreSQL, ClickHouse, MinIO, and Apache Arrow Flight for fast columnar queries and object storage.

Data Ownership

Contributors retain ownership, associate cite-able DOIs per dataset, and can modify or update their data at any time.

Cross-Cluster Federation

Integrate any number of voluntary data centers connected through the SynDB API endpoint for distributed queries.

Multiple Interfaces

Web UI, REST API, and CLI. Access your data however you prefer, from browser to terminal.

ETL Pipeline

Automated ingestion from major connectomics data sources with validation, transformation, and graph precomputation.

Horizontal Scalability

Kubernetes-native deployment with ClickHouse sharding for scaling across data centers and workloads.

Datasets

Curated collection of synaptic connectome and neuro-anatomical datasets across model organisms and human tissue.

FlyWireHemibrainMANCMale-CNSFANCMICrONSH01BANCSpine Morphometry

Get Started

Explore the platform, read the documentation, or dive into the source code.